Introduction: Previous studies have shown a lack of required biostatistical knowledge among residents. There are few data on the departmental variation of biostatistical knowledge among residents. Furthermore, there is a paucity of data comparing residents and medical students. We hypothesized that residents’ biostatistical knowledge varies across departments and there are individual characteristics that may serve as predictors for increased knowledge. Methods: We surveyed residents and medical students rotating at our institution. The survey tool included questions on demographics, prior biostatistics exposure, educational history, and confidence in biostatistics. The remainder of the survey included a previously validated 17-question biostatistics quiz. Descriptive statistics are used to summarize the responses. Univariate and bivariate analyses were done to compare means and calculate correlation, respectively. Multivariate analysis was performed to derive independent predictors of increased knowledge.Results: A total of 218 participants completed the survey. Twenty-five (11.5%) were medical students and 193 (88.5%) were residents. The overall mean (SD) percent correct on the quiz was 48.3% (14.5%), and average correct was not different between students and residents(50.4% SD 13.2% vs 48.2% SD 14.6%, p = 0.45). There was a significant difference in the mean scores across all departments (range: 39.2-58.1%, p
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