TCT-164 Immediate and Pre-Discharge Post-TAVR Invasive and Echocardiographic Hemodynamics of Sapien 3 Resilia, Sapien 3 Ultra and Self-Expanding Valves
Recommended Citation
Mahmood S, Madanat L, Renard B, Hanson I, Palomo A, Schwann T, Vivacqua A, Kindzelski B, Villablanca P, Khalili H, Chhabra K, Alakhras H, Ahmad E, Abbas A. TCT-164 Immediate and Pre-Discharge Post-TAVR Invasive and Echocardiographic Hemodynamics of Sapien 3 Resilia, Sapien 3 Ultra and Self-Expanding Valves. J Am Coll Cardiol 2024; 84(18):B397.
Document Type
Conference Proceeding
Publication Date
10-29-2024
Publication Title
J Am Coll Cardiol
Abstract
Background: Studies suggest similar immediate post transcatheter aortic valve replacement (TAVR) invasive and echocardiographic gradients across TAVR platforms, despite lower discharge echocardiographic gradients in self-expanding valves (SEV) vs balloon-expandable valves (BEV) Sapien 3 Ultra (S3U). Lower discharge echocardiographic gradients have been reported with BEV Sapien 3 Resilia (S3R) vs S3U. We compared immediate post-TAVR invasive and echocardiographic gradients and discharge echocardiographic gradients in BEV S3U, BEV S3R, and SEV. Methods: Consecutive patients who underwent TAVR were included. Immediate post-TAVR invasive gradients were compared with concomitant and discharge echocardiographic gradients across BEV S3U, BEV S3R, and SEV. Results: A total of 166 patients were analyzed (77 S3U, 61 S3R, 28 SEV). Post-TAVR, invasive gradients were lower than echocardiographic gradients in all valves (P value < 0.001 for all). Across all valves, immediate post-TAVR invasive (S3U; 0.21 ± 0.9 mm Hg, S3R; 0.1 ± 0.5 mm Hg, SEV; 0.21 ± 0.70 mm Hg, P = 0.81) and echocardiographic gradients (S3U; 5.0 ± 2.4 mm Hg, S3R; 5.0 ± 2.7 mm Hg, SEV; 6.0 ± 2.3 mm Hg, P = 0.40) were similar. Discharge echocardiographic gradients were highest in S3U valves (12 ± 4.8 mm Hg) vs S3R (10 ± 4.5 mm Hg) and SEV (9 ± 4.4 mm Hg) with P value = 0.002 (Figure 1A and B). [Formula presented] Conclusion: Lower discharge echocardiographic gradients in BEV S3R and SEV vs BEV S3U were noted despite similar immediate post-TAVR invasive and echocardiographic gradients. Valve design and flow states impact discharge echocardiographic gradients but not post-TAVR invasive and echocardiographic gradients. Categories: STRUCTURAL: Valvular Disease: Aortic.
Volume
84
Issue
18
First Page
B397
