Emerging medical treatments for hidradenitis suppurativa
Lyons AB, Shabeeb N, Nicholson CL, Braunberger TL, Peacock A, and Hamzavi IH. Emerging medical treatments for hidradenitis suppurativa. J Am Acad Dermatol 2020.
Journal of the American Academy of Dermatology
Hidradenitis suppurativa (HS) is a chronic inflammatory disease affecting intertriginous skin areas, and it is characterized by recurrent painful episodes of inflammatory drainage. While the pathophysiology of HS is not fully understood, recent research points to an imbalance of cytokines as a contributing factor to the associated symptoms of purulent drainage and sinus tract formation. HS lesions are often characterized by a superimposed pathogenic/commensal bacterial infection that can improve with targeted antibiotic therapy. New medical treatments have emerged in recent years, many of which specifically work against a variety of pro-inflammatory mediators associated with HS. These newer, specified treatment options, in conjunction with surgery and lasers, are thought to provide positive outcomes and an overall improvement in quality of life in patients with HS.
ePub ahead of print