Weathering the storm: A case of thyroid storm refractory to conventional treatment benefiting from therapeutic plasma exchange.
Wyble AJ, Moore SC, and Yates SG. Weathering the storm: A case of thyroid storm refractory to conventional treatment benefiting from therapeutic plasma exchange. J Clin Apher 2018.
J Clin Apher
Thyroid storm is a severe manifestation of thyrotoxicosis characterized by systemic organ dysfunction secondary to a hypermetabolic state. Although antithyroid drugs, steroids, beta-blockers, antipyretics, and cholestyramine are the standard of care, some patients inadequately respond to these conventional therapies. Therapeutic plasma exchange has been previously utilized as a treatment modality in patients with a poor response to routine therapies or with contraindications to them. Herein, we report our experience with the management of a case of thyroid storm refractory to conventional treatment but responsive to therapeutic plasma exchange.
Medical Subject Headings
Disease Management; Humans; Plasma Exchange; Salvage Therapy; Thyroid Crisis; Treatment Outcome