Dynamic Presentations of Recurrent Post-Transplant Lymphoproliferative Disorder in a Heart Transplant Recipient: A Rare Case Study

Authors

Avi Toiv, Henry Ford HealthFollow
Kevin B. Harris, Henry Ford HealthFollow
Muhammad Z. Khan, Henry Ford HealthFollow
Brian K. Theisen, Henry Ford HealthFollow
Adarsh Varma, Henry Ford HealthFollow
Christopher Fain, Henry Ford HealthFollow
Nirmal Kaur, Henry Ford HealthFollow

Recommended Citation

Toiv A, Harris KB, Khan MZ, Theisen BK, Varma A, Fain C, and Kaur N. Dynamic Presentations of Recurrent Post-Transplant Lymphoproliferative Disorder in a Heart Transplant Recipient: A Rare Case Study. ACG Case Rep J 2024; 11(11):e01554.

Document Type

Article

Publication Date

11-1-2024

Publication Title

ACG Case Rep J

Abstract

Post-transplant lymphoproliferative disorders (PTLD) are complications that arise from post-transplantation immunosuppressive therapy. Although Epstein-Barr virus (EBV) viremia is often seen in PTLD, it is not a definitive feature for diagnosis. We report a rare case of recurrent PTLD in a 26-year-old heart transplant recipient on high-dose tacrolimus who presented with emesis, fatigue, and bloody diarrhea. Although substantial EBV viremia was seen in the first PTLD episode, the current episode was a gastrointestinal manifestation with barely detectable circulating EBV. The patient's history of gastrointestinal disease delayed definitive diagnosis, which was later established through endoscopy and biopsy sample analysis.

PubMed ID

39568982

Volume

11

Issue

11

First Page

01554

Last Page

01554