Henry Ford Hospital Medical Journal


A patient is described in whom sarcoidosis of the mediastinal lymph nodes was found during the course of acute idiopathic thrombocytopenic purpura. The association of these two diseases should be differentiated from the more commonly seen thrombocytopenia of hypersplenic origin, occurring during the disseminated stage of sarcoidosis, in which granulomatous involvement of an enlarged spleen is found. An elevated serum IgM immunoglobulin level was present. These observations possibly strengthen the concept that an immunological disorder plays a significant role in sarcoidosis.