Growth hormone (GH) is a major hormone of the anterior pituitary gland. Once established, its secretion continues throughout life. GH was first recognized in 1866 as a factor controlling growth. More recently, it has been demonstrated as a vital regulator of fat, carboyhdrate and protein metabolism. In fact, GH influence on the intermediary metabolism is the major mechanism by which growth and development are regulated. Numerous hormonal and nonhormonal factors have been shown to modify the basic pattern of GH synthesis and secretion. In this article we have reviewed some of these nonhormonal factors.
Zafar, M. Saeed; Mellinger, Raymond C.; and Morrow, Lewis B.
"Hypophyseal Growth Hormone: I. Control of Secretion,"
Henry Ford Hospital Medical Journal
: Vol. 18
Available at: https://scholarlycommons.henryford.com/hfhmedjournal/vol18/iss2/9