A 55-year-old man had a large superior mediastinal tumor producing obstructive symptoms. The tumor was removed through an upper median sternotomy incision. It was found to be composed of so-called Hurthle-cells, which are of thyroid origin, and the pathologist's interpretation was that it was of low grade malignancy. A pulmonary metastatic nodule was excised five years later, and 8 1/2 years after the original operation, a nodule was removed from a pectoral muscle. The patient lived 12 years and then expired with multiple metastases, but he was relatively asymptomatic until the last few months.
Lam, Conrad R.
"Malignant Intrathoracic Hurthle-Cell Tumor: Report of a case with 12-year survival following three palliative operations,"
Henry Ford Hospital Medical Journal
: Vol. 22
Available at: https://scholarlycommons.henryford.com/hfhmedjournal/vol22/iss2/6