This study presents the clinical features, roentgenographic manifestations, pathological features, abnormal laboratory studies, treatment and prognosis of 157 cases of osteogenic sarcoma. The series is the fifth largest ever reported. The authors favor prompt surgical ablation followed by controlled intensive chemotherapy as a prophylactic or combined chemotherapy and radiation therapy for metastatic osteogenic sarcoma. All case reports but one present rare or unusual situations.
Wu, Kent K.; Guise, Edwin R.; Frost, Harold M.; and Mitchell, C. Leslie
"Osteogenic sarcoma: Report of one hundred and fifty-seven cases,"
Henry Ford Hospital Medical Journal
: Vol. 24
Available at: https://scholarlycommons.henryford.com/hfhmedjournal/vol24/iss4/6