Liver cell adenoma and focal nodular hyperplasia have been recognized as rare benign tumors. Their relationship with the use of oral contraceptives has been suggested since 1973. At Henry Ford Hospital, we have had four patients, ages 19, 23, 25,and 30, on oral contraceptives who presented with different clinical pictures suggesting acute abdomen. A hepatic tumor was suspected preoperatively in one patient, was found at laparotomy for biliary tract disease in two other cases, while the fourth patient presented with acute intra-abdominal hemorrhage. Hepatic resection was performed successfully in all with no mortality. The clinical presentation and diagnostic and surgical management will be discussed.
Maciel, V.; Allen, H.; and Grodsinsky, C.
"Primary hepatic tumors in women on oral contraceptives,"
Henry Ford Hospital Medical Journal
: Vol. 25
Available at: https://scholarlycommons.henryford.com/hfhmedjournal/vol25/iss4/7