Positron emitting radionuclides have unique properties that make them nearly ideal as radioactive tracers for in vivo metabolic studies. Using positron emission tomographic (PET) scanning and positron-labeled radiopharmaceuticals, one can study local glucose metabolism in tissues, blood flow, oxygen utilization, protein synthesis, and many other functions noninvasively in normal subjects and patients who have various diseases. A review of some of these techniques and the relative advantages and problems associated with the PET approach is presented.
Keyes, John W. Jr.
"Current Concepts of Metabolic Functional Imaging with Positron Emitters,"
Henry Ford Hospital Medical Journal
: Vol. 33
Available at: https://scholarlycommons.henryford.com/hfhmedjournal/vol33/iss2/14