Sociodemographic factors in patients continuing warfarin vs those transitioning to direct oral anticoagulants.
Schaefer J, Sood S, Haymart B, Gu X, Kong X, Kline-Rogers E, Almany S, Kozlowski J, Krol G, Kaatz S, Froehlich J, Barnes G. Sociodemographic factors in patients continuing warfarin vs those transitioning to direct oral anticoagulants.. Blood Adv 2017; 1(26):2536-2540.
Clinical factors and patient preferences are important for selecting oral anticoagulants for venous thromboembolism (VTE) and atrial fibrillation (AF). The relative association of sociodemographic factors with anticoagulant use is unknown. We evaluated a prospective cohort to compare sociodemographic variables in patients who continued on warfarin for AF or VTE to those who transitioned to 1 of the direct oral anticoagulants (DOACs). Adult patients, newly started on warfarin, were enrolled through 6 anticoagulation clinics across Michigan. Of 8468 patients, 53.3% had AF, 45.6% had VTE, and 1.1% had both. Of these, 696 (8.2%) switched from warfarin to a DOAC. There were no significant differences between switchers and nonswitchers for percentage of time with a therapeutic international normalized ratio on warfarin, urban-rural residence status, or health insurance. Switchers were more often white (83.3% vs 77.7%;