Multicenter, retrospective cohort study of antimycobacterial treatment-related harms among patients with non-tuberculosis
Recommended Citation
Veve MP, Kenney RM, Aljundi AM, Dierker MS, Athans V, Shallal AB, and Patel N. Multicenter, retrospective cohort study of antimycobacterial treatment-related harms among patients with non-tuberculosis Mycobacterium infections in the United States. Antimicrob Agents Chemother 2025; 69(4):0159624.
Document Type
Article
Publication Date
4-2-2025
Publication Title
Antimicrobial agents and chemotherapy
Abstract
Non-tuberculosis mycobacteria (NTM) are extensively drug-resistant organisms that require long-term therapy. The study purpose was to quantify the incidence of and risk factors for antimycobacterial-associated adverse drug events (ADEs) in persons with NTM infections receiving outpatient therapy. A multicenter, retrospective cohort was performed of persons with NTM infections who received antimycobacterial treatment from 2013 to 2024. Inclusion criteria were age ≥18 years, ≥1 month of outpatient treatment, and ≥1 follow-up outpatient visit within 3 months of index encounter.
Medical Subject Headings
Adult; Aged; Aged, 80 and over; Female; Humans; Male; Middle Aged; Acute Kidney Injury; Aminoglycosides; Anti-Bacterial Agents; Clostridium Infections; Macrolides; Mycobacterium Infections, Nontuberculous; Nontuberculous Mycobacteria; Retrospective Studies; Risk Factors; Thrombocytopenia; United States
PubMed ID
40035548
ePublication
ePub ahead of print
Volume
69
Issue
4
First Page
0159624
Last Page
0159624
