Quinidine hypersensitivity: a side effect of a forgotten antiarrhythmic
El-Khatib L, Alrayes H, Sallam O, and Elbanna A. Quinidine hypersensitivity: a side effect of a forgotten antiarrhythmic. BMJ Case Rep 2020; 13(8).
BMJ Case Rep
Quinidine is one of the oldest antiarrhythmics known. Over the years, its use has decreased along with its side effects. Our case describes a 69-year-old woman with recurrent resistant ventricular tachycardia on Quinidine and Amiodarone who presented with acute liver toxicity. Drug-induced liver toxicity was at the top of our differential diagnosis list. Taking multiple factors into consideration, a decision was made to discontinue Quinidine, the patient's symptoms and lab abnormalities resolved within 1 week, yielding the diagnosis of Quinidine hypersensitivity.