Colonic malakoplakia
Recommended Citation
Saleem A, Hussain M, Schechter S, and Sturm MB. Colonic malakoplakia. BMJ Case Rep 2025; 18(3).
Document Type
Article
Publication Date
3-25-2025
Publication Title
BMJ Case Rep
Abstract
Colonic malakoplakia is a rare granulomatous inflammatory condition that can cause abdominal pain, diarrhoea and rectal bleeding and be associated with colon adenocarcinoma. Chronic bacterial infections with defective lysosomal activity in macrophages are possible causes for malakoplakia. We present a case report of asymptomatic colonic malakoplakia in an otherwise healthy woman undergoing a screening colonoscopy for colorectal cancer. Limited case reports and treatment guidance are available for colonic malakoplakia with only a few dozen cases in the literature. Given the potential morbidity and mortality associated with this condition, we emphasise the importance of thorough diagnostic and therapeutic evaluation even in asymptomatic patients.
Medical Subject Headings
Humans; Malacoplakia; Female; Colonoscopy; Colonic Diseases; Middle Aged; Diagnosis, Differential
PubMed ID
40132942
Volume
18
Issue
3
