Impact of Ethnicity on the Outcomes of Acute Pancreatitis: Insights From US National Inpatient Sample Database
Recommended Citation
Jaan A, Farooq U, Malik S, Chaudhary A, Inayat F, Chatha U, Khan A, Cryer B, Mahmood S. Impact of Ethnicity on the Outcomes of Acute Pancreatitis: Insights From US National Inpatient Sample Database. Am J Gastroenterol 2023; 118(10):S12.
Document Type
Conference Proceeding
Publication Date
10-1-2023
Publication Title
Am J Gastroenterol
Abstract
Introduction: Epidemiological studies using administrative or retrospective data have highlighted racial differences in the susceptibility and progression of pancreatitis. However, limited research has been conducted to investigate the impact of race on the outcome of acute pancreatitis (AP). Methods: Using the 2017-2020 National Inpatient Sample (NIS) database and the International Classification of Diseases, Tenth Revision, Clinical Modifications (ICD-10- CM) codes, we identified adult patients (aged ≥18 years) who were admitted with a principal diagnosis of AP. Using Whites as the reference category, we compared the outcomes of AP in African Americans, Hispanics, and Asians. Multivariate logistic regression models were used to compare the different races. Results: We reviewed 219,835 admissions for AP. After adjusting for confounding variables, we found that African Americans had the lowest mortality rates (aOR 0.76, P< 0.01) when compared to Whites (Table 1). Additionally, African Americans had the lowest odds of septic shock (aOR 0.53, P< 0.01), acute respiratory distress syndrome (ARDS) (aOR 0.64, P< 0.01), need for mechanical ventilation (aOR 0.53, P< 0.01), and intensive care unit (ICU) admission (aOR 0.54, P< 0.01) compared to White patients. Furthermore, African Americans had shorter lengths of hospital stay (adjusted mean difference [aMD] 0.54, P< 0.01) and incurred lower average hospitalization charges (aMD -$6,844, P< 0.01) than Whites. In contrast, the Hispanic population demonstrated the lowest odds of developing acute kidney injury (AKI) (aOR 0.93, P< 0.01), portal venous thrombosis (aOR 0.51, P< 0.01), and the need for pancreatic necrosectomy (aOR 0.67, P< 0.01). Conclusion: Our study found notable racial disparities in the outcomes of AP. African Americans demonstrated lower mortality rates, lower odds of critical complications, shorter hospital stays, and lower hospitalization charges than Caucasians. These findings warrant further investigation of racial differences to achieve equitable healthcare outcomes.
Volume
118
Issue
10
First Page
S12
