Management of status epilepticus in adults
Ramadan AR, and Varelas PN. Management of status epilepticus in adults. J Clin Outcomes Manag 2017; 24(8):371-384.
J Clin Outcomes Manag
Objective: To review the management of status epilepticus (SE). Methods: Review of the literature. Results: SE is a relatively common condition that accounts for 3% to 5% of all emergency department evaluations for seizure disorders and occurs in 2% to 16% of all epilepsy patients. The 3 most common etiologies are low levels of antiepileptic drugs, remote symptomatic etiologies, and cerebrovascular accidents. The majority of SEs are convulsant, but there is growing awareness of non-convulsive SEs, which can be diagnosed only via electroencephalogram. Management, which must be initiated at the earliest possible time, has evolved to incorporate pre-hospital measures and 4 treatment stages, with supportive measures and benzodiazepine administration remaining the mainstay initially and followed by older and newer antiepileptic drugs and anesthetics for resistant cases. Conclusion: SE is a neurological emergency that still carries significant mortality and morbidity if not treated immediately and properly.