Magnetic resonance imaging and cell-based neurorestorative therapy after brain injury

Document Type

Article

Publication Date

1-1-2016

Publication Title

Neural Regen Res

Abstract

Restorative cell-based therapies for experimental brain injury, such as stroke and traumatic brain injury, substantially improve functional outcome. We discuss and review state of the art magnetic resonance imaging methodologies and their applications related to cell-based treatment after brain injury. We focus on the potential of magnetic resonance imaging technique and its associated challenges to obtain useful new information related to cell migration, distribution, and quantitation, as well as vascular and neuronal remodeling in response to cell-based therapy after brain injury. The noninvasive nature of imaging might more readily help with translation of cell-based therapy from the laboratory to the clinic.

PubMed ID

26981068

Volume

11

Issue

1

First Page

7

Last Page

14

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