Title

Targeting Triple Negative Breast Cancer with a Small-sized Paramagnetic Nanoparticle.

Document Type

Article

Publication Date

10-1-2016

Publication Title

J Nanomed Nanotechnol

Abstract

There is no available targeted therapy or imaging agent for triple negative breast cancer (TNBC). We developed a small-sized dendrimer-based nanoparticle containing a clinical relevant MRI contrast agent, GdDOTA and a NIR fluorescent dye, DL680. Systemic delivery of dual-modal nanoparticles led to accumulation of the agents in a flank mouse model of TNBC that were detected by both optical and MR imaging.

PubMed ID

28018751

Volume

7

Issue

5

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