Ramirez-Zamora A, Eisinger RS, Haider SA, Youn Y, Shin D, Molho ES, and Pilitsis JG. Pallidal deep brain stimulation and intraoperative neurophysiology for treatment of poststroke hemiballism. Ann Clin Transl Neurol 2018; 5(7):865-869.
Ann Clin Transl Neurol
Deep brain stimulation is a recognized and effective treatment for several movement disorders. Nevertheless, the efficacy of this intervention on abnormal movements secondary to structural brain pathologies is less consistent. In this report, we describe a case of hemiballism-hemichorea due to a peripartum ischemic stroke-treated with deep brain stimulation of the globus pallidus internus. Patient observed marked improvement in her symptoms at long-term follow-up. Neurophysiologic data revealed lower globus pallidus internus firing rates compared to other hyperkinetic disorders. Pallidal deep brain stimulation is a plausible option for medically refractory hemiballism-hemichorea and cumulative data from multiple centers may be used to fully evaluate its efficacy.