Title

A Novel COL1A1-CAMTA1 Rearrangement in Cranial Fasciitis

Document Type

Article

Publication Date

3-19-2020

Publication Title

International journal of surgical pathology

Abstract

Cranial fasciitis is an uncommon benign fibroblastic tumor, generally histologically identical to nodular fasciitis. It develops almost exclusively in children. Cranial fasciitis manifests clinically as a painless rapidly growing solitary nodule in the head and neck area, frequently eroding the underlying bone. Thus, this entity is often confused with aggressive lesions such as sarcomas, both clinically and radiologically. Histopathologic examination is essential to differentiate between cranial fasciitis and fibrohistiocytic or even sarcomatous lesions observed in children. In this article, we present a case of cranial fasciitis with intracranial extension in a 2-year-old boy. Although in nodular fasciitis, we present a novel COL1A1-CAMTA1 fusion in this lesion.

PubMed ID

32192385

ePublication

ePub ahead of print

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