Abou Shaar R, Zia S, Alhamar M, Romano T, Shaw B, Keller C, and Friedman BJ. Salivary gland hyalinizing clear cell carcinoma with cutaneous metastasis: a rare and deceptive tumor. J Cutan Pathol 2020.
Journal of cutaneous pathology
Clear cell carcinoma (CCC) is an uncommon malignant tumor of minor salivary glands. It characteristically has a low-grade morphology and a favorable outcome by most reports. An EWSR1-ATF1 fusion can be detected in the majority of cases. We present a rare case of CCC which had an aggressive course with the development of cutaneous metastases. Practicing dermatopathologists should be aware of this tumor given its low-grade appearance and histologic resemblance to other primary cutaneous adnexal and metastatic neoplasms.
ePub ahead of print