Operative strokes after repair of acute type a dissections: predisposing factors and implications
Weisberg A, Nemeh H, Kabbani LS, Shepard AD, Van Harn M, Morgan J, Borgi J. Operative strokes after repair of acute type a dissections: predisposing factors and implications. Journal of cardiovascular surgery 2019; .
Journal of cardiovascular surgery
BACKGROUND: Type A aortic dissection is a surgical emergency with a high morbidity and mortality. Strokes occur in up to 25% and are among the most feared complications. This study aims to evaluate factors linked to stroke development and the implications of strokes on outcomes.
METHODS: Patients from 2000-2014 were stratified based on the development of stroke. Factors were compared between the groups using chi-square or Fisher's exact tests for categorical variables, and independent two-group t-tests for continuous variables. Impact on survival at 30 days, 1 and 5 years were evaluated using the life-test method.
RESULTS: 200 patients were analyzed. 40 (20%) developed a stroke. Preoperative factors associated with stroke were female gender (34% vs 14% p=0.01), presentation with shock (32% vs 17%; p=0.035), and history of stroke (64% vs 17%; p < 0.001). Femoral cannulation was the only technical variable associated with stroke (49% vs 32%; p=0.035). Stroke patients had a higher rate of pneumonia (41% vs 11%; p
CONCLUSIONS: Patients who developed stroke after type A dissection repair had higher complication rates and a higher mortality rate at 30 days, 1 year, and 5 years. Femoral cannulation was the only technical factor associated with a higher rate of strokes.
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