Al-Jumayli M, Brown SL, Chetty IJ, Extermann M, and Movsas B. The Biological Process of Aging and the Impact of Ionizing Radiation. Semin Radiat Oncol 2022; 32(2):172-178.
Seminars in radiation oncology
Ionizing radiation is used to create models of accelerated aging because the processes of aging and radiation injury share common elements. In this chapter we review the biological processes of aging and the similarities and impact of ionizing radiation on those processes. The information draws on data from laboratory studies and from epidemiology studies of radiation exposure victims. The chapter reviews the effects of radiation on DNA, cells, and organs systems on aged adults. The science of aging and the effect of radiation on the aging process are areas of active research and our understanding is evolving.
Medical Subject Headings
Adult; Aging; Biological Phenomena; Humans; Middle Aged; Radiation Exposure; Radiation Injuries; Radiation, Ionizing