Effect of mandatory 6-month waiting period on waitlist and transplant outcomes in patients with hepatocellular carcinoma.
Nagai S, Kitajima T, Yeddula S, Salgia R, Schilke R, Abouljoud MS, and Moonka D. Effect of mandatory 6-month waiting period on waitlist and transplant outcomes in patients with hepatocellular carcinoma. Hepatology 2020.
Hepatology (Baltimore, Md.)
OPTN/UNOS policy mandates a 6-month waiting period before exception scores are granted to liver transplant candidates with hepatocellular carcinoma (HCC). This study aims to evaluate waitlist and post-transplant outcomes, in HCC patients, before and after implementation of the 6-month waiting rule. We examined two groups from the UNOS registry; Group 1 (pre 6-month rule) comprised patients registered as transplant candidates with HCC from Jan. 1, 2013 to Oct. 7, 2015 (n=4,814). Group 2 (post 6-month rule) comprised patients registered from Oct. 8, 2015 to Jun. 30, 2018 (n=3,287). As expected, the transplant probability was higher in the first six months after listing in Group 1 than Group 2 at 42.0% vs 6.3% (P
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