Precision surgery for hepatocellular carcinoma
Recommended Citation
Magyar CTJ, Rajendran L, Li Z, Banz V, Vogel A, O'Kane GM, Chan AC, and Sapisochin G. Precision surgery for hepatocellular carcinoma. Lancet Gastroenterol Hepatol 2025.
Document Type
Article
Publication Date
4-1-2025
Publication Title
Lancet Gastroenterol Hepatol
Abstract
Hepatocellular carcinoma arises in the setting of cirrhosis in most cases, requiring multidisciplinary input to define resectability. In this regard, more precise surgical management considers patient factors and anatomical states, including resection margins, tumour biology, and perioperative therapy. Together with advances in surgical techniques, this integrated approach has resulted in considerable improvements in patient morbidity and oncological outcomes. Despite this, recurrence rates in hepatocellular carcinoma remain high. As the systemic treatment landscape in hepatocellular carcinoma continues to evolve and locoregional options are increasingly used, we review current and future opportunities to individualise the surgical management of patients with hepatocellular carcinoma.
Medical Subject Headings
Humans; Carcinoma, Hepatocellular; Liver Neoplasms; Hepatectomy; Precision Medicine; Neoplasm Recurrence, Local; Margins of Excision
PubMed ID
39993401
ePublication
ePub ahead of print
Volume
10
Issue
4
First Page
350
Last Page
368
