Khwaja F. Haq Raja C. Chakinala Mohammad A. Siddiqui Shantanu Solanki Muhammad Ali Zubair Khan Abhishek Bhurwal Khawaja S. Haq Anam S. Burney Faiza Bhatti
Henry Ford Health System
05-01-2019
Introduction: Sphincter of Oddi plays an important physiologic role by controlling the flow of biliary and pancreatic secretions through the ampulla of Vater into the duodenum. Sphincter of Oddi dysfu..
Introduction: Sphincter of Oddi plays an important physiologic role by controlling the flow of biliary and pancreatic secretions through the ampulla of Vater into the duodenum. Sphincter of Oddi dysfunction (SOD), either from stenosis or dyskinesis, has been associated with complications such as biliary pain, idiopathic recurrent pancreatitis, and post-ERCP pancreatitis. Limited epidemiological data exists on the number of hospitalizations, demographic variations, cost of care, and comorbidity measures associated with SOD.Methods: We analyzed the National Inpatient Sample (NIS) database for all hospitalizations with SOD (ICD-9 code 576.5) as primary or secondary diagnosis during the period from 2005-2011. NIS is the largest all-payer inpatient care database in the United States, containing data on more than 7 million hospital stays. Its large sample size is ideal for developing national and regional estimates. Statistical significance of variation in hospitalizations, patient demographics, comorbidity measures, and cost of care during the study period were determined using Cochran-Armitage trend test.Results: Between 2005 and 2011, hospitalizations with SOD increased from 600 to 980 (p