Treatment of severe hyponatremia in patients with kidney failure: Role of continuous venovenous hemofiltration with low-sodium replacement fluid
Recommended Citation
Yessayan L, Yee J, Frinak S, Szamosfalvi B. Treatment of severe hyponatremia in patients with kidney failure: Role of continuous venovenous hemofiltration with low-sodium replacement fluid. American Journal of Kidney Diseases 2014; 64(2):305-310.
Document Type
Article
Publication Date
1-1-2014
Publication Title
American Journal of Kidney Diseases
Abstract
Patients with hypervolemic hyponatremia and kidney failure pose a special therapeutic challenge. Hemodialysis to correct volume overload, azotemia, and abnormal electrolyte levels will result in rapid correction of serum sodium concentration and place the patient at risk for osmotic demyelination syndrome. We present a patient with acute kidney injury and severe hypervolemic hypotonic hyponatremia (serum sodium < 100 mEq/L) who was treated successfully with continuous venovenous hemofiltration. This teaching case illustrates the limitations of hemodialysis and demonstrates how to regulate the sodium correction rate by single-pool sodium kinetic modeling during continuous venovenous hemofiltration. Two methods to adjust the replacement fluid to achieve the desired sodium concentration are outlined. © 2014 by the National Kidney Foundation, Inc.
PubMed ID
24792353
Volume
64
Issue
2
First Page
305
Last Page
310
