Recommended Citation
Basir MB, Pinto DS, Ziaeian B, Khandelwal A, Cowger J, Suh W, and Althouse A. Mechanical circulatory support in acute myocardial infarction and cardiogenic shock: Challenges and importance of randomized control trials. Catheter Cardiovasc Interv 2021.
Document Type
Article
Publication Date
3-7-2021
Publication Title
Catheterization and cardiovascular interventions
Abstract
BACKGROUND: Acute myocardial infarction (AMI) complicated by cardiogenic shock (CS) is associated with significant morbidity and mortality.
METHODS: We provide an overview of previously conducted studies on the use of mechanical circulatory support (MCS) devices in the treatment of AMI-CS and difficulties which may be encountered in conducting such trials in the United States.
RESULTS: Well powered randomized control trials are difficult to conduct in a critically ill patient population due to physician preferences, perceived lack of equipoise and challenges obtaining informed consent.
CONCLUSIONS: With growth in utilization of MCS devices in patients with AMI-CS, efforts to perform well-powered, randomized control trials must be undertaken.
PubMed ID
33682260
ePublication
ePub ahead of print
