Use of the gaia guidewires in a contemporary multicenter registry of chronic total occlusion percutaneous coronary intervention
Karacsonyi J, Alaswad K, Hatem R, Karmpaliotis D, Jaffer F, Yeh R, Choi J, Toma C, Doing A, Uretsky B, Patel M, Mahmud E, Moses J, Kirtane A, Parikh M, Ali Z, Martinez-Parachini J, Karatasakis A, Danek B, Tajti P, Khalili H, Rangan B, Ungi I, Thompson C, Banerjee S, Brilakis E. Use of the gaia guidewires in a contemporary multicenter registry of chronic total occlusion percutaneous coronary intervention. Catheter Cardiovasc Interv. 2017;89:S54-S55.
Background: We sought to examine the use of thecomposite core hydrophilic Gaia guidewires inchronic total occlusion (CTO) percutaneous coronaryintervention (PCI). Methods: Baseline clinical and angiographic characteristics and procedural outcomes of 847 CTO PCIs performed between 2015 and 2016 at 9 US centers in 825 patients were evaluated. Results: The mean patient age was 65.1±10 years and 87% were men. The Gaiaguidewires were increasingly being used (30.5% antegrade and 7.6% retrograde crossing attempts in2015 vs 47.9% antegrade and 20.5% retrograde crossing attempts in 2016; p<0.0001 for both respectively). In antegrade crossing the Gaia wires were used in more complex lesions with higher Japanese chronic total occlusion scores (2.76±1.18 vs. 2.25±1.32, p<.0001) and were associated with lower technical and procedural success rates (79.1% vs. 87.0%, p=0.006; 77.6% vs. 85.8%, p= 0.007) but similar incidence of major adverse events (MACE: 3.56% vs. 2.64%, p=0.501). In retrograde crossing useof the Gaia wires was associated with similar technical and procedural success rates (80.5% vs. 77.3%, p=0.645; 68.3% vs. 72.9%, p=0.0536), but higher incidence of MACE (17.07% vs. 5.48%, p=0.006). Conclusion: In a contemporary, multicenterregistry Gaia guidewires are commonly and increasingly being used, especially in more complex cases and are associated with high technical and procedural success rates. (Table presented).