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Submissions from 2019

Inadequate response to UDCA among PBC patients under routine care in the US: Rising serum bilirubin even in the normal range is a risk factor and subsequent clinical follow-up differs based on treatment response, Stuart C Gordon, Talan Zhang, C L. Bowlus, K D. Lindor, R J. Romanelli, I V. Haller, H Anderson, J J. Vanwormer, J A. Boscarino, M A. Schmidt, Y G. Daida, A Sahota, J Vincent, K H. Wu, Sheri Trudeau, Christina Melkonian, Loralee B Rupp, and Mei Lu

Effect of treatment of hepatitis B patients with tenofovir disoproxil or entecavir on risk of hepatocellular cancer death in a U.S. Cohort, Stuart C Gordon, Yueren Zhou, Jian Li, Loralee B Rupp, J A. Boscarino, Y G. Daida, M A. Schmidt, Sheri Trudeau, and Mei Lu

Complications of chronic hepatitis B: Prevalence and disparities in a US health system cohort 2006-2016, Mei Lu, Yueren Zhou, Jian Li, Loralee B. Rupp, J A Boscarino, Y G Daida, MA Schmidt, Sheri Trudeau, and Stuart C Gordon

Submissions from 2018

Effect of SVR on liver-related and all-cause hospitalization of patients with chronic HCV infection: The chronic hepatitis cohort study (CHECS), 2014-16., R Augustine, J Xing, PR Spradling, AC Moorman, Loralee B Rupp, Stuart C Gordon, Mei Lu, JA Boscarino, MA Schmidt, Y Daida, SD Holmberg, and EH Teshale

Digital cognitive behavioral therapy for insomnia reduces incident depression at one-year follow-up., Philip Cheng, Gabriel Tallent, A Luik, Edward L Peterson, Kieulinh Michelle Tran, Brian K Ahmedani, D Adler, Thomas Roth, and Christopher L Drake

Admixture mapping of total serum IgE in African American subjects from CAAPA., M Daya, A Shetty, NM Rafaels, VE Ortega, ER Bleecker, DA Meyers, C Ober, L Keoki Williams, MA Taub, TH Beaty, I Ruczinski, RA Mathias, and KC Barnes

Comparative analysis of direct-acting antiviral regimens across Hepatitis C genotypes and clinical characteristics among patients under routine clinical care in the US., Stuart C Gordon, Jia Li, SD Holmberg, AC Moorman, PR Spradling, EH Teshale, JA Boscarino, Y Daida, MA Schmidt, Kuan-Han Hank Wu, Loralee B Rupp, Talan Zhang, MPH Trudeau, and Mei Lu

Serum bilirubin within normal range is associated with an increasing risk of mortality in patients with primary biliary cholangitis regardless of ursodeoxycholic acid treatment., Stuart C Gordon, C Rodriguez, RJ Romanelli, IV Haller, H Anderson, JJ VanWormer, JA Boscarino, MA Schmidt, Y Daida, AK Sahota, JL Vincent, CL Bowlus, Talan Zhang, Sheri Trudeau, Jia Li, Christina Melkonian, Kuan-Han Hank Wu, Loralee B Rupp, and Mei Lu

Joint test of allelic dosage and local ancestry identifies INTS3 as new susceptibility gene for asthma among african american individuals., Hongsheng Gui, Albert M Levin, Shujie Xiao, Maozhou Yang, J Yang, Samantha Hochstadt, Kyle Whitehouse, Alexis Carlton, Dean Rynkowski, David E Lanfear, R Kumar, EG Burchard, and L Keoki Williams

Epidemiological trends of chronic hepatitis b among routine clinical care patients in the US (2006-2015)., Mei Lu, SD Holmberg, AC Moorman, PR Spradling, EH Teshale, JA Boscarino, Y Daida, Yueren Zhou, Loralee B Rupp, Talan Zhang, Sheri Trudeau, and Stuart C Gordon

Hepatitis C patients with HIV co-infection demonstrate unique liver-related complications and health behaviors compared to HCV mono-infected patients., Mei Lu, Norman Markowitz, Yueren Zhou, Kuan-Han Hank Wu, Loralee B Rupp, Sheri Trudeau, JA Boscarino, MA Schmidt, YG Daida, and Stuart C Gordon

HIV co-infection is associated with increased liver complications and reduced mental health among patients with chronic hepatitis B., Mei Lu, Norman Markowitz, Yueren Zhou, Kuan-Han Hank Wu, Loralee B Rupp, Sheri Trudeau, Jia Li, JA Boscarino, MA Schmidt, YG Daida, and Stuart C Gordon

Whole-Genome sequencing of pharmacogenetic drug response in racially diverse children with asthma., ACY Mak, MJ White, WL Eckalbar, ZA Szpiech, SS Oh, M Pino-Yanes, D Hu, P Goddard, S Huntsman, J Galanter, A Chen Wu, BE Himes, S Germer, JM Vogel, KL Bunting, C Eng, S Salazar, KL Keys, J Liberto, TJ Nuckton, TA Nguyen, DG Torgerson, PY Kwok, Albert M. Levin, JC Celedón, E Forno, H Hakonarson, PM Sleiman, A Dahlin, KG Tantisira, ST Weiss, D Serebrisky, E Brigino-Buenaventura, HJ Farber, K Meade, MA Lenoir, PC Avila, S Sen, SM Thyne, W Rodriguez-Cintron, CA Winkler, A Moreno-Estrada, K Sandoval, JR Rodriguez-Santana, R Kumar, Keoki L. Williams, N Ahituv, E Ziv, MA Seibold, RB Darnell, N Zaitlen, RD Hernandez, and EG Burchard

Presence of advanced liver disease concurrent with initial diagnosis of Hepatitis C virus (HCV) infection among patients in the chronic hepatitis cohort study (CHECS) 2014-16: Missed opportunities for intervention., AC Moorman, J Xing, Loralee B Rupp, Stuart C Gordon, Mei Lu, PR Spradling, JA Boscarino, Y Daida, MA Schmidt, SD Holmberg, and EH Teshale

Effect of tobacco exposure on inhaled corticosteroid response in minority children with asthma., L Samedy, S Oh, A Davis, D Serebrisky, E Brigino-Buenaventura, F Lurmann, J Ford, JR Rodriguez-Santana, K Meade, LN Borrell, MA Lenoir, PC Avila, R Kumar, R Chapela, S Sen, W Rodriguez, S Thyne, M Siebold, Keoki L. Williams, and EG Burchard

Severe liver disease outcomes and mortality among patients with chronic hepatitis B who completed an in-depth health and behavior survey in 2012., PR Spradling, J Xing, AC Moorman, Loralee B Rupp, Stuart C Gordon, JA Boscarino, MA Schmidt, Y Daida, Mei Lu, EH Teshale, and SD Holmberg

Submissions from 2017

Genome-wide association study of asthma in individuals of mixed african ancestry reveals a novel association on chromosome 2q14., M Daya, NM Rafaels, S Chavan, M Boorgula, HR Johnston, J Wilson, L Keoki Williams, C Rotimi, C Ober, D Meyers, E Bleeker, VE Ortega, J Knight-Madden, NN Hansel, H Watson, MU Faruque, GM Dunston, L Caraballo, MI Araujo, EG Burchard, M Taub, I Ruczinski, T Beaty, ZS Qin, R Mathias, and KC Barnes

Health outcomes among surveyed patients infected with hepatitis C in the Chronic Hepatitis Cohort Study (CHeCS), MG Hofmeister, J Xing, AC Moorman, Loralee B Rupp, Stuart C Gordon, JA Boscarino, MA Schmidt, YH Daida, Mei Lu, EH Teshale, SD Holmberg, and PR Spradling

Does Hepatitis C eradication lead to improved glucose metabolism, renal and cardiovascular outcomes in diabetic patients?, Jia Li, Stuart C Gordon, Loralee B Rupp, Talan Zhang, Sheri Trudeau, SD Holmberg, AC Moorman, PR Spradling, EH Teshale, JA Boscarino, MA Schmidt, Y Daida, and Mei Lu

Impact of sustained virological response on incidence of type 2 diabetes in hepatitis c patients., Jia Li, Talan Zhang, Stuart C Gordon, Loralee B Rupp, Sheri Trudeau, SD Holmberg, AC Moorman, PR Spradling, EH Teshale, JA Boscarino, MA Schmidt, YH Daida, and Mei Lu

Epidemiologic trends and treatment survival benefits in a US cohort of patients with primary biliary cholangitis (PBC)., Mei Lu, Yueren Zhou, I Haller, R Romanelli, JJ VanWormer, CV Rodriguez, H Anderson, JA Boscarino, MA Schmidt, Y Daida, AK Sahota, J Vincent, CL Bowlus, KD Lindor, Talan Zhang, Sheri Trudeau, Jia Li, Loralee B Rupp, and Stuart C Gordon

The relationship between hypoglycemia severity and work productivity loss and costs among type 2 diabetes patients, M Pawaskar, K Iglay, E A. Witt, S Rajpathak, S S. Engel, and L K. Williams

Submissions from 2016

Long-term fibrosis and viral level progression among treated and untreated patients with chronic hepatitis B, Jia Li, Stuart C. Gordon, Loralee B Rupp, Talan Zhang, J Boscarino, C Trinacty, M Schmidt, A Moorman, S Holmberg, and Mei Lu

Hepatitis C complications: prevalence and disparities in a large US cohort 2006-2014, Mei Lu, Stuart C. Gordon, Jia Li, Loralee B. Rupp, Yueren Zhou, Anne C. Moorman, Phillip Spardling, Eyasu H. Teshale, Joseph A. Boscarino, Yihe Daida, Mark A. Schmidt, Sheri Trudeau, and Scott D. Holmberg

Improving risk prediction in heart failure: MAGGIC plus natriuretic peptides, Alexander T. Michaels, Ryhm Radjef, Ruicong She, Bin Liu, Edward L. Peterson, Yigal Pinto, Keoki L. Williams, Hani Sabbah, and David Lanfear

Performance of MAGGIC score in African Americans compared to whites, Ryhm Radjef, Alexander Michaels, Edward L. Peterson, Ruicong She, Bin Liu, Keoki Williams, Hani Sabbah, and David Lanfear

PAI-1, early life infections and asthma risk, exacerbations, and reduced lung function, Kumar Rajesh, Seong Ho Cho, Jin Young Min, Joseph Kang, Wendy Chan, Dong-Young Kim, Sam Oh, Dara Torgerson, Maria del Mar Del-Pino-Yanes, Donglei Hu, Saunak Sen, Scott Huntsman, Celeste Eng, Harold J. Farber, William Rodriguez-Santana, Denis Serebrisky, Shannon Thyne, Luisa Borrell, Keoki L. Williams, Max Seibold, Esteban Gonzalez Burchard, and Pedro C. Avila

Uptake of and factors associated with direct-acting anti-viral therapy among patients infected with hepatitis C virus in the Chronic Hepatitis Cohort Study, 2014-2015, Philip R. Spradling, Jian Xing, Loralee B. Rupp, Anne C. Moore, Stuart C. Gordon, Mei Lu, Eyasu H. Teshale, Joseph A. Boscarino, Yihe Daida, Mark A. Schmidt, and Scott D. Holmberg

Preliminary clinical outcome data among patients with hepatitis C virus infection receiving direct-acting antiviral therapy in the Chronic Hepatitis Cohort Study, 2014-2015, Philip R. Spradling, Jian Xing, Loralee B. Rupp, Anne C. Moorman, Stuart C. Gordon, Mei Lu, Eyasu H. Teshale, Joseph A. Boscarino, Yihe Daida, Mark A. Schmidt, and Scott D. Holmberg

Alcohol use disorder among chronic hepatitis C patients: prevalence and treatment outcomes, CHeCS, 2006-2013, Eyasu H. Teshale, Yuna Zhang, Anne C. Moorman, Philip R. Spradling, Scott D. Holmberg, Loralee B. Rupp, Mei Lu, Stuart C. Gordon, Joseph A. Boscarino, Yihe Daida, and Mark A. Schmidt

Submissions from 2015

Characteristics of patients tested for hepatitis C and intervention costs in the best-C study, Joanne E. Brady, Danielle Liffmann, Anthony K. Yartel, Natalie B. Kil, Alex D. Federman, Cynthia E. Jordan, Omar I. Massoud, David R. Nerenz, Kimberly Ann Brown, Bryce Smith, Claudia Vellozzi, and David B. Rein

HBV-related cirrhosis in the Chronic Hepatitis Cohort Study (CHeCS), Stuart C. Gordon, Loralee B. Rupp, Joseph A. Boscarion, Mark A. Schmidt, Connie M. Trinacty, Lois Lamerato, Nancy Oja-Tebbe, and Mei Lu

Peripheral metabolite pattern in heart failure patients is an independent predictor of survival, David E. Lanfear, Stephen Gardell, Abert Levin, Jia Li, Keoki Williams, Hani Sabbah, and Nicole Zeld

Metabolomic patterns in heart failure patients vary across demographic and clinical factors, David E. Lanfear, Hani N. Sabbah, Abert M. Levin, Yun Wang, Ruicong She, Jia Li, Keoki Williams, Stephen Gardell, and Nicole Zeld

Imputation from 328 African Ancestry genomes reveals new associations with asthma in DPP10, Hironori Masuko, Nicholas M. Rafaels, Lili Huang, Sameer Chavan, James G. Wilson, Keoki L. Williams, Lorraine B. Ware, Carole Ober, Deborah A. Meyers, Tina V. Hartert, Marilyn Foreman, Jean G. Ford, Esteban Gonza Burchard, Eugene R. Bleecker, Georgia Dunston, Margaret Taub, Terri H. Beaty, Ingo Ruczinski, Rasika A. Mathias, and Kathleen C. Barnes

Mediators of disparities in survival among patients with non-small cell lung cancer, Anish Mehta, Shannon Stock, Stacy Gray, David Nerenz, John Z. Ayanian, and Nancy L. Keating

A multi-ethnic genome-wide association study of 21 000 cases and 95 000 controls identifies 11 novel genetic variants associated with atopic dermatitis, L Paternoster, M Standl, H Baurecht, J Waage, M Hotze, J A. Curtin, K Bonnelykke, D Glass, C Tian, E Melen, P Sleiman, B Feenstra, M Pino-Yanes, H T. den Dekker, M Bustamante, I Marenholz, B Jacobsson, A D. Irvine, A C. Alves, M M. Groen-Blokhuis, A Franke, M Ferreira, M Tamari, N Probst-Hensch, Keoki Williams, B Raby, E G. Burchard, C Ober, S Barton, J Holloway, C-J Xu, J Thyssen, C Wang, D Jarvis, F Xiao, D P. Strachan, S J. Brown, J Heinrich, D M. Evans, and S Weidinger

How well does whole genome sequencing improve ability to detect association with asthma in candidate genes compared to existing GWAS platforms in African American populations?, Nicholad M. Rafaels, Henry R. Johnston, Lili Huang, Sameer Chavan, James G. Wilson, Keoki L. Williams, Lorraine B. Ware, Carole Ober, Deborah A. Meyers, Tina V. Hartert, Marilyn Foreman, Jean G. Ford, Esteban Gonza Burchard, Eugene R. Bleecker, Margaret Taub, Terri H. Beaty, Ingo Ruczinski, Rasika A. Mathias, and Kathleen C. Barnes

A genome-wide association study of allergic rhinitis in 216 361 individuals identifies several novel susceptibility loci and increases knowledge on genetic pathways and cell types involved in disease etiology, J E. Waage; M Standl; L Paternoster; C Tian; A James; R Granell; S Bunyavanich; R Myers; E Kreiner-Moller; T Palviainen; M den Dekker; F Ruschendorf; A Barreto-Luis; T Ahluwalia; N Vilor-Tejedor; J Curtin; Australian Asthma Genetics Consortium; A Alves; A Abdellaoui; C Wang; Abert Levin; J Kaprio; Y-A Lee; I Bruske; C Flores; E Nohr; J Sunyer; D Boomsma; C Pennel; Keoki Williams; S Weiss; A Simpson; A Custovic; M Ferreira; L Duijts; M-R Jarvelin; C Ober; J Henderson; D Hinds; D Strachan; The EArly, Genetics; Lifecourse Epidemiology Consortium,Asthma, Allergy and Atopy; H Bisgaard; and K Bonnelykke