The Effects of Postoperative Intralesional Corticosteroids in the Prevention of Recurrent Earlobe Keloids: A Multispecialty Retrospective Review
Gold DA, Sheinin R, Jacobsen G, Jones LR, Ozog DM. The Effects of Postoperative Intralesional Corticosteroids in the Prevention of Recurrent Earlobe Keloids: A Multispecialty Retrospective Review. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 2018; 44(6):865-869.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
BACKGROUND: Effective treatment of keloids is challenging because the recurrence rate after surgical excision is high. Data on the best treatment practices are lacking.
OBJECTIVE: To investigate the recurrence rate after surgical excision of earlobe keloids based on a postoperative intralesional corticosteroid injection protocol.
MATERIALS AND METHODS: Retrospective chart review was performed from January 1, 2005, to March 31, 2016, of patients who had excision of ear keloids within the departments of dermatology, otorhinolaryngology, and plastic surgery. The number of postoperative injections was recorded, recurrence was reported by the patient, and the efficacy of an injection protocol was evaluated.
RESULTS: There were 277 charts reviewed. Appropriate data were available for 184 patients. A statistically significant difference was found with recurrence associated with a lower number of injections (p < .001). Keloids were more likely to recur if they were not treated with a planned serial injection protocol (p < .001) or if they were treated outside the department of dermatology (p < .001).
CONCLUSION: Intralesional corticosteroid injection after surgical excision of earlobe keloids statistically minimizes the risk of recurrence.
Medical Subject Headings
Adolescent; Adult; Child; Ear, External; Female; Follow-Up Studies; Glucocorticoids; Humans; Injections, Intralesional; Keloid; Male; Postoperative Care; Recurrence; Retrospective Studies; Treatment Outcome