Document Type

Article

Publication Date

9-1-2021

Publication Title

Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology

Abstract

Photoaging induced by both ultraviolet and visible light has been shown to lead to increased inflammation and dysregulation of the extracellular matrix. Standardized extract of the Polypodium leucotomos fern, PLE, possesses anti-inflammatory and antioxidant properties, and has been shown to potentially mitigate photoaging through various mechanisms. This comprehensive review presents the data available on the effects of P. leucotomos extract on UV and VL-induced photoaging in vitro as well as in vivo in murine and human models.

Medical Subject Headings

Animals; Anti-Inflammatory Agents; Antioxidants; Humans; Light; Plant Extracts; Polypodium; Skin; Skin Aging; Sunscreening Agents; Ultraviolet Rays

PubMed ID

34449075

ePublication

ePub ahead of print

Volume

20

Issue

9

First Page

1229

Last Page

1238

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