Pourang A, Dourra M, Ezekwe N, Kohli I, Hamzavi I, and Lim HW. The potential effect of Polypodium leucotomos extract on ultraviolet- and visible light-induced photoaging. Photochem Photobiol Sci 2021.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology
Photoaging induced by both ultraviolet and visible light has been shown to lead to increased inflammation and dysregulation of the extracellular matrix. Standardized extract of the Polypodium leucotomos fern, PLE, possesses anti-inflammatory and antioxidant properties, and has been shown to potentially mitigate photoaging through various mechanisms. This comprehensive review presents the data available on the effects of P. leucotomos extract on UV and VL-induced photoaging in vitro as well as in vivo in murine and human models.
Medical Subject Headings
Animals; Anti-Inflammatory Agents; Antioxidants; Humans; Light; Plant Extracts; Polypodium; Skin; Skin Aging; Sunscreening Agents; Ultraviolet Rays
ePub ahead of print