Comorbid autoimmune diseases in a cohort of patients with vitiligo
Gill L, Zarbo A, Isedeh PN, Jacobsen G, Lim HW, Hamzavi I. Comorbid autoimmune diseases in a cohort of patients with vitiligo. J Am Acad Dermatol 2015; 72(5):AB219.
J Am Acad Dermatol
Background: Vitiligo has been reported to be associated with autoimmune diseases. However, few large-scale studies have been conducted to quantify the burden of autoimmune disease in patients with vitiligo. Objective: To determine the prevalence of comorbid autoimmune diseases in patients with vitiligo seen at the Henry Ford Hospital Department of Dermatology in Detroit, Michigan, during a period of almost 11 years. Methods: Using the International Classification of Diseases, 9th revision code 709.01, we searched the Henry Ford Health System Medical Record Database to identify 1873 patients with vitiligo seen between January 2002 and November 2012. We manually reviewed all 1873 electronic medical records to validate the diagnosis of vitiligo and collect data. Patients were excluded if they did not have at least 2 dermatology notes (N = 595) and if they were never diagnosed with vitiligo by a dermatologist (N = 180), resulting in a final study population of 1098 patients with vitiligo. As designed a priori, we assessed the prevalence of comorbid autoimmune diseases in these patients. Results: The final study population included 1098 patients with vitiligo. Nearly 20% had at least 1 comorbid autoimmune disease. Compared to the general US population, we found a higher prevalence of thyroid disease (12.9% of those 12 years or older, P