Graft-versus-host disease following deceased donor liver transplant
Recommended Citation
Putchakayala K, Skorupski S, Farhan S, Chaffins M, Ilias S, Pahari H, Collins K, Nagai S, Abouljoud M. Graft-versus-host disease following deceased donor liver transplant. Am J Transplant 2017; 17:783-784.
Document Type
Conference Proceeding
Publication Date
2017
Publication Title
Am J Transplant
Abstract
We reviewed our institutional experience with graft-versus-host disease(GVHD) following orthotopic liver transplantation (OLT). All OLT from 10/1/2013-10/1/2016 were reviewed. Five cases of GVHD were identified. Recipient-Donor characteristics (Table presented). All had NASH cirrhosis. Donor-recipient age difference was 8 to 32 years. Despite donor BMI and liver weight 2.0-2.4kg, biopsies found 2.0kg) and recipient lymphocyte depletion (ALC 0) to allow donor lymphocytes to persist and activate. A high level of suspicion and prompt biopsy/DNA testing are essential. Treatment modalities must be balanced with the risks of rejection and infection, but remission and survival are possible.
Volume
17
First Page
783
Last Page
784
