Prevalence of diabetes in patients with osteoporotic hip fractures: A tertiary care center fracture consultation service experience
Huq S, Das L, Bhan A, Honasoge M, Rao SD. Prevalence of diabetes in patients with osteoporotic hip fractures: A tertiary care center fracture consultation service experience. Journal of Bone and Mineral Research 2018; 33(Supplement 1).
Journal of Bone and Mineral Research
Osteoporotic fractures are a major cause of disability, morbidity and mortality. Both diabetes mellitus (DM) and hip fractures contribute to morbidity and mortality. Although DM is a known risk factor for osteoporotic fractures and the risk of hip fracture is increased 1.3-2.1 folds in DM, little is known about the prevalence of DM in patients admitted to hospital for hip fractures.The aim of our study was to determine the prevalence of DM among patients admitted to hospital with acute proximal femur fractures over a five year period (January 1st, 2011 to December 31st 2016). The electronic health records of 163 patients with acute hip fractures in our tertiary care setting were reviewed to determine the prevalence of DM in patients with hip fractures.There were 72 Caucasians (44%), 52 African Americans (32%), 4 Hispanics (2%), 1 Asian, 1 Arab and 33 patients (20%) who had no race documented. The prevalence of DM was 36%, four fold higher than in the general population, and the majority (93%) were Typ 2 DM. Both serum 25-hydroxyvitamin D and PTH levels were numerically lower in DM patients compared to non-DM patients (19.3 ± 12.2 Vs. 22.3 ± 12.9 ng/ml, and 62.3 ± 38.2 Vs. 87 ± 103 pg/ml, respectively).It is postulated that fracture risk is increased in patients with DM most likely due to increased glycation of collagen leading to decreased plasticity and bone strength without necessarily affecting bone density. In addition lower PTH levels in DM imply a low bone turnover state resulting in “aged” bone, which compromises bone strength. Further studies are needed to confirm our finding of very high prevalence of DM in hip fracture patients.