Addressing sex-based disparities in solid organ transplantation in the United States - a conference report

Document Type

Article

Publication Date

3-1-2023

Publication Title

American journal of transplantation

Abstract

Solid organ transplantation provides the best treatment for end-stage organ failure, but significant sex-based disparities in transplant access exist. On June 25, 2021, a virtual multidisciplinary conference was convened to address sex-based disparities in transplantation. Common themes contributing to sex-based disparities were noted across kidney, liver, heart, and lung transplantation, specifically the existence of barriers to referral and wait listing for women, the pitfalls of using serum creatinine, the issue of donor/recipient size mismatch, approaches to frailty and a higher prevalence of allosensitization among women. In addition, actionable solutions to improve access to transplantation were identified, including alterations to the current allocation system, surgical interventions on donor organs, and the incorporation of objective frailty metrics into the evaluation process. Key knowledge gaps and high-priority areas for future investigation were also discussed.

Medical Subject Headings

Female; Humans; Frailty; Healthcare Disparities; Kidney; Organ Transplantation; Tissue and Organ Procurement; Tissue Donors; United States; Waiting Lists

PubMed ID

36906294

Volume

23

Issue

3

First Page

316

Last Page

325

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