Title

A Retrospective Study Analyzing the Appropriateness of Initial Treatment of

Document Type

Article

Publication Date

1-1-2018

Publication Title

Gastroenterol Res Pract

Abstract

Background:

Methods: This is a retrospective study of adult patients admitted with CDI and any underlying active malignancy at Beaumont Hospital, Royal Oak, Michigan, from January 2008 to December 2014. Inclusion criteria included age > 18 years old, polymerase chain reaction- (PCR-) proven CDI, and active malignancy.

Results: 197 patients were included in the final analysis. 44.8% of the metronidazole group required escalation of therapy compared to 15.2% in the vancomycin group (

Discussion: Our results support the initial use of vancomycin or a combination (metronidazole and vancomycin) versus metronidazole in patients with CDI and active malignancy.

PubMed ID

29991944

Volume

2018

First Page

7192728

Last Page

7192728

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