Artificial differences in Clostridium difficile infection rates associated with disparity in testing
Kamboj M, Brite J, Aslam A, Kennington J, Babady NE, Calfee D, Furuya Y, Chen D, Augenbraun M, Ostrowsky B, Patel G, Mircescu M, Kak V, Tuma R, Karre TA, Fry DA, Duhaney YP, Moyer A, Mitchell D, Cantu S, Hsieh C, Warren N, Martin S, Willson J, Dickman J, Knight J, Delahanty K, Flood A, Harrington J, Korenstein D, Eagan J, and Sepkowitz K. Artificial differences in clostridium difficile infection rates associated with disparity in testing. Emerg Infect Dis 2018; 24(3):584-587.
Emerg Infect Dis
In 2015, Clostridium difficile testing rates among 30 US community, multispecialty, and cancer hospitals were 14.0, 16.3, and 33.9/1,000 patient-days, respectively. Pooled hospital onset rates were 0.56, 0.84, and 1.57/1,000 patient-days, respectively. Higher testing rates may artificially inflate reported rates of C. difficile infection. C. difficile surveillance should consider testing frequency.
Medical Subject Headings
Bacteriological Techniques; Clostridium Infections; Clostridium difficile; Health Status Disparities; Hospitalization; Hospitals; Humans; Nucleic Acid Amplification Techniques; Public Health Surveillance