Title

Diltiazem Induced Bullous Leukocytoclastic Vasculitis

Authors

Elian D. Abou Asala, Henry Ford Health SystemFollow
David J. Gelovani, Henry Ford Health SystemFollow
Fiona Clowney, Henry Ford Health SystemFollow
Megan Scott, Henry Ford Health SystemFollow
Jasmine Omar, Henry Ford Health SystemFollow

Files

Program

Internal Medicine

Training Level

Resident PGY 1

Institution

Henry Ford Hospital

Abstract

Diltiazem is a calcium ion cellular influx inhibitor approved by the U.S. Food and Drug Administration for the management of hypertension and chronic stable angina. Diltiazem is commonly used off label for chronic ventricular rate control in atrial fibrillation. Very few cases of widespread cutaneous vasculitis have been described in association with diltiazem since 1988. We report on a patient developing diffuse petechiae with overlying palpable purpura and tense bullae in both lower extremities, which progressed to the thighs, buttocks, abdomen, and upper extremities 6 days after starting diltiazem for management of atrial fibrillation. Skin biopsy revealed leukocytoclastic vasculitis.

Presentation Date

5-2020

Recommended Citation

Abou Asala, Elian D.; Gelovani, David J.; Clowney, Fiona; Scott, Megan; and Omar, Jasmine, "Diltiazem Induced Bullous Leukocytoclastic Vasculitis" (2020). Case Reports. 125.
https://scholarlycommons.henryford.com/merf2020caserpt/125