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Internal Medicine

Training Level

Resident PGY 1


Henry Ford Macomb


This is a case of a pleasant 81 year-old male who presented to the ED complaining of chest pain with activity for the past 3-4 weeks. He reports of chest pain with minimal exertion of walking across the parking lot to the car. This has been a substantial change from his baseline, he currently works as a mason. He was referred to the ED by his primary care physician after having abnormal lab result showing low hemoglobin of 7.6. During the admission he underwent work up of his chest pain and symptomatic anemia. The patient’s anemia was attributed to intestinal arteriovenous malformations seen in the cecum and ascending colon during colonoscopy. He had a 2-D ECHO showing severe aortic valve stenosis. The patient was diagnosed with Heyde syndrome which is the association acquired von Willebrand deficiency with aortic stenosis and gastrointestinal angiodysplasia. Here we discuss the pathophysiology of Heyde syndrome and the role of TAVR in treatment of our patient.

Presentation Date


The Role of Transcatheter Aortic Valve Replacement in Heyde Syndrome