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Resident PGY 3
Henry Ford Hospital
Gout is a systemic disease characterized by monosodium urate crystal deposition triggering inflammation throughout the body. The authors present a case of a 37-year-old female who presented with bilateral eyelid and canthal lesions. The patient had a tan spherical lesion on her left upper lid, a circumscribed flesh-colored nodule at her left medial canthus, and a more pigmented lesion at her right lateral canthus. Following complete excisional biopsy of all lesions, histopathologic analysis revealed pink fibrillary material with histiocytic reaction in all 3 lesions consistent with gout. Only 6 prior cases of eyelid or canthal tophi have been reported, and this study adds a new case to the few existing reports. The authors emphasize that gouty tophi should remain on the differential for eyelid lesions.
Mikkilineni, Shravani and Schlachter, Dianne M., "Rare case of gout manifesting as bilateral eyelid lesions" (2020). Case Reports. 49.