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Resident PGY 2
Henry Ford Hospital
A 55-year-old man presented with a right sided orbital mass causing globe displacement and diplopia. The mass was excised and histopathology findings were consistent with a respiratory epithelial orbital cyst, a type of choristoma. Choristomas represent normal tissue growing in an abnormal location. This unusual orbital cyst may originate from a rest of respiratory epithelium during development, or through seeding of paranasal sinus respiratory tissue from trauma. This isolated cyst is distinct from a mucocele, which is more common in the orbit and is comprised of ciliated respiratory epithelium in continuity with a chronically obstructed paranasal sinus. The clinical course may be complicated by infection, rupture with inflammation, and progressive mass effect leading to globe displacement and compressive optic neuropathy. These complications necessitate surgical excision.
Jin, Man Li (Elina) and George, Christian, "Respiratory Epithelial Orbital Cyst: A Rare Cause of Globe Displacement" (2020). Case Reports. 74.