Document Type

Article

Publication Date

12-2-2017

Publication Title

BMC nephrology [electronic resource]

Abstract

BACKGROUND: Hyperchloremia is common in critically ill septic patients. The impact of hyperchloremia on the incidence of acute kidney injury (AKI) is not well studied. We investigated the association between hyperchloremia and AKI within the first 72 h of intensive care unit (ICU) admission.

METHODS: 6490 ICU adult patients admitted with severe sepsis or septic shock were screened for eligibility. Exclusion criteria included: AKI on admission, baseline estimated glomerular filtration rate (eGFR)/min/1.73 m

RESULTS: A total of 1045 patients were available for analysis following the implementation of eligibility criteria: 303 (29%) had hyperchloremia (Cl

CONCLUSIONS: Hyperchloremia occurs commonly among critically ill septic patients admitted to the ICU, but does not appear to be associated with an increased risk for AKI within the first 72 h of admission.

Medical Subject Headings

Acute Kidney Injury; Aged; Aged, 80 and over; Chlorides; Cohort Studies; Critical Illness; Female; Humans; Intensive Care Units; Male; Middle Aged; Retrospective Studies; Sepsis; Water-Electrolyte Imbalance

PubMed ID

29197350

Volume

18

Issue

1

First Page

346

Last Page

346

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