Epidemiology and Risk Factors for Bacteremia in Pediatric and Adolescent Patients

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J Pharm Pract


BACKGROUND: Epidemiology and risk factors for bacteremia in pediatric and adolescent patients have not been fully elucidated.

OBJECTIVE: The purpose of this study was to identify primary causative agents of bacteremia in pediatric and adolescent patients and associated risk factors. We hypothesized that these would be different than those seen in adults.

PATIENTS AND METHODS: This retrospective cohort, epidemiologic evaluation included patients admitted to a tertiary referral center from January 01, 2013, to December 31, 2015. Patientsincluded; the first positive culture per organism per patient was analyzed. The primary outcome was to determine the most frequent causative organisms of bacteremia; the secondary outcome was an evaluation of risk factors for acquiring staphylococcal bacteremia.

RESULTS: A total of 913 isolates were evaluated, including 92 unique organisms. The most frequently identified were

CONCLUSIONS: Although epidemiology of organisms associated with pediatric and adolescent bacteremia was similar to adults, risk factors were different than seen in that population. Further understanding of these risk factors may be helpful in developing preemptive infection control strategies in patients at risk.

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ePub ahead of print