Title

A MLC-based inversely optimized 3D spatially fractionated grid radiotherapy technique

Document Type

Article

Publication Date

12-1-2015

Publication Title

Radiotherapy and oncology

Abstract

This study presents a MLC-based, 3D grid-therapy technique with characteristics of both 3D-conformal-radiotherapy and grid-therapy. It generates a brachytherapy-like dose distribution, with D50% of 20, 9.8, 5.4 and 2.9-Gy, for the spheres, target, 1 cm-outershell and 2 cm-outershell, respectively. It may provide a strategy to deliver ablative doses to large tumors safely.

Medical Subject Headings

Dose Fractionation, Radiation; Humans; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Conformal

PubMed ID

26277434

Volume

117

Issue

3

First Page

483

Last Page

486

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