A MLC-based inversely optimized 3D spatially fractionated grid radiotherapy technique.
Jin JY, Zhao B, Kaminski JM, Wen N, Huang Y, Vender J, Chetty IJ, and Kong FS. A MLC-based inversely optimized 3D spatially fractionated grid radiotherapy technique. Radiother Oncol 2015; 117(3):483-486.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
This study presents a MLC-based, 3D grid-therapy technique with characteristics of both 3D-conformal-radiotherapy and grid-therapy. It generates a brachytherapy-like dose distribution, with D50% of 20, 9.8, 5.4 and 2.9-Gy, for the spheres, target, 1 cm-outershell and 2 cm-outershell, respectively. It may provide a strategy to deliver ablative doses to large tumors safely.
Medical Subject Headings
Dose Fractionation, Radiation; Humans; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Conformal