Time trends and predictors of heart dose from breast radiation therapy in a large consortium of community and academic practices.
Feng M, Moran JM, Benedetti L, Boike TP, Dryden D, Fraser C, Griffith KA, Gustafson GS, Haywood J, Jagsi R, Matuszak MM, Nurushev TS, Radawski JD, Speers C, Walker EM, Hayman JA, and Pierce LJ. Time trends and predictors of heart dose from breast radiation therapy in a large consortium of community and academic practices. Int J Radiat Oncol Biol Phys 2016; 96(2s):E15-e16.
Int J Radiat Oncol Biol Phys
Observational studies suggest that the risk of cardiac toxicity increases with increasing radiation dose to the heart, without a threshold for this effect. Although a recent systematic review summarized heart doses in the published literature, less is known about the range of heart doses delivered in routine practice in the United States today. The goal of this study was to assess the current state of cardiac sparing in a large prospective observational cohort, and to determine how cardiac dose varies by practice setting, technique, and patient characteristics.