Title

Incidental Uptake of 18F-Fluciclovine by Type AB Thymoma

Document Type

Article

Publication Date

2-1-2022

Publication Title

Clinical nuclear medicine

Abstract

ABSTRACT: Biochemical recurrence of prostate cancer, detected by a rising PSA, may reflect intraprostatic or extraprostatic recurrence. 18F-Fluciclovine (Axumin), a synthetic amino acid substrate in tumor metabolism, has frequently been used for to localize recurrent prostate cancers. We present a 71-year-old man with biochemical recurrence of prostate cancer but no convincing imaging findings on 18F-fluciclovine PET/CT. Of note, however, was an incidental uptake within the anterior mediastinum, which was found on biopsy to be a type AB thymoma. With this, we stress that awareness of false-positive uptake patterns is crucial for accurate diagnosis of recurrent prostate cancer.

Medical Subject Headings

Aged; Carboxylic Acids; Cyclobutanes; Humans; Male; Neoplasm Recurrence, Local; Positron Emission Tomography Computed Tomography; Prostatic Neoplasms; Thymoma; Thymus Neoplasms

PubMed ID

35006112

Volume

47

Issue

2

First Page

116

Last Page

116

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