Title

Radiological diagnosis of drop metastases from paediatric brain tumours using combination of 2D and 3D MRI sequences.

Document Type

Article

Publication Date

10-1-2017

Publication Title

Clinical radiology

Abstract

AIM: To evaluate spinal magnetic resonance imaging (MRI) examinations using a combination of two-dimensional (2D) and three-dimensional (3D) MRI sequences for diagnosis of drop metastases.

MATERIALS AND METHODS: Fifty-five paediatric patients with primary brain tumours were evaluated for drop metastases at initial presentation using spinal MRI including sagittal 2D T1-weighted (W) contrast-enhanced (+C), axial 3D T1W+C volumetric interpolated breath-hold (VIBE), and sagittal 3D T2W SPACE (Sampling Perfection with Application optimised Contrasts using different flip angle Evolutions).

RESULTS: The MRI false-negative rate was 4%, and cerebrospinal fluid (CSF) false-negative rate was 16% (p=0.07). The 3D T1W+C VIBE increased the number of drop metastases detected in 42% of patients. Drop metastases were more conspicuous in 25% of patients on 3D T2W SPACE.

CONCLUSION: Spinal MRI examinations including 2D and 3D sequences demonstrate characteristics that may improve radiological diagnosis of drop metastases.

Medical Subject Headings

Adolescent; Brain Neoplasms; Child; Child, Preschool; Female; Humans; Imaging, Three-Dimensional; Infant; Magnetic Resonance Imaging; Male; Meningeal Neoplasms; Retrospective Studies

PubMed ID

28545686

Volume

72

Issue

10

First Page

e13-902

Last Page

e19

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