Persistent vs resolved intrauterine growth restriction: A retrospective, cohort study assessing neonatal outcome.
Lupea I, Saeed H, and Roberts R. Persistent vs resolved intrauterine growth restriction: A retrospective, cohort study assessing neonatal outcome. Obstet Gynecol 2018; 131:9S.
Introduction: Intrauterine growth restriction (IUGR) is a com-mon complication of pregnancy that has been shown to be associated with adverse perinatal outcomes. Once the diagnosis is made, antenatal monitoring becomes intensive and can cause parental stress and anxiety. The purpose of this study is to evaluate and compare neonatal outcomes in pregnancies which were diagnosed with IUGR that subsequently resolve in comparison to those with persistent IUGR. Methods: This is a retrospective, cohort of singleton pregnancies complicated by IUGR (EFW, 10th percentile) from 2013-2017 from Henry Ford Health System in Detroit, MI. There are approximately 1000 new IUGR diagnoses every year at Henry Ford. Neonatal out-comes were compared in pregnancies that IUGR resolved versus those with IUGR persisted throughout the pregnancy. Results: The primary neonatal outcomes that will be compared between the two cohorts are: fetal birth weight, fetal APGAR scores (1 and 5 minutes), fetal umbilical cord gases, necrotizing enterocolitis, need for respiratory support, and length of stay in NICU. Secondary outcomes will assess route of delivery and gestational age at delivery. A descriptive analysis of the results obtained will be presented. Conclusion: Growth restriction has been shown to be a risk factor for adverse perinatal outcomes. Our study aims to analyze if this stands true for those pregnancies that had growth restriction that spontaneously resolved. The results may impact future guidelines in regards to antenatal testing for the pregnancies with spontaneous resolution of the fetal growth restriction.